http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107823915-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01D15-3804 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01D15-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-22 |
| filingDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107823915-B |
| titleOfInvention | Alkali-resistant affinity chromatography medium |
| abstract | The scheme relates to an alkali-resistant affinity chromatography medium, which takes polyamide microspheres as an inner core, linear polysaccharide molecules are crosslinked on the surfaces of the polyamide microspheres, hydroxyl groups in the linear polysaccharide molecules and amide groups exposed on the surfaces of the polyamide microspheres are simultaneously bonded with allyl-2, 3-epoxypropyl ether, and the allyl-2, 3-epoxypropyl ether is also connected with a ligand and is used for separating and purifying protein products; the allyl-2, 3-epoxypropyl ether and the polyamide inner core cross-linked with the straight-chain polysaccharide molecules generate double bonding under the acidic condition, the stability of the ligand can be increased after the ligand is connected, the ligand is not easy to fall off or degrade in the using and cleaning processes of the affinity chromatography medium, and the alkaline tolerance degree of the affinity chromatography medium obtained by the invention to sodium hydroxide is improved. |
| priorityDate | 2017-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.