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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-14
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-14
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filingDate 2017-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107823189-B
titleOfInvention Potassium chloride sustained-release pellet and preparation method and application thereof
abstract The invention relates to a potassium chloride sustained-release pellet, a preparation method and application thereof. The invention provides a potassium chloride sustained-release pellet, which comprises a pellet core, a potassium chloride main drug layer, an isolation layer, a sustained-release coating layer and a color coating layer. The release amount of the potassium chloride sustained-release pellet prepared by the invention is less than or equal to 25% in 1 hour, less than or equal to 70% in 4 hours, and less than or equal to 85% in 8 hours. The invention uses the sustained-release coating material, and by accurately controlling the sustained-release speed of the potassium chloride in the potassium chloride sustained-release pellet, the drug release is stable, the expected blood concentration is obtained, the long action time can be maintained, the burst release phenomenon does not exist, and the adverse reactions such as stimulation to gastric mucosa and the like can be avoided.
priorityDate 2017-11-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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