http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107814809-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D493-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4192 |
| filingDate | 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107814809-B |
| titleOfInvention | A kind of psoralen derivative and purposes of the triazole containing phenyl |
| abstract | The present invention relates to the psoralen derivative and purposes of a kind of triazole containing phenyl, which is 4-methyl-7-hydroxycoumarin (intermediate 1)；4- methyl -7- (2- oxo) benzene ethoxy coumarin (intermediate 2)；5- methyl -3- phenyl psoralen (intermediate 3)；7- oxo -3- phenyl - 7H Furans [3,2-g] chromene -5- formaldehyde (intermediate 4)；5- methylol -3- phenyl - 7H Furans [3,2-g] chromene -7- ketone (intermediate 5)；5- bromomethyl -3- phenyl - 7H Furans [3,2-g] chromene -7- ketone (intermediate 6)；5- azido-methyl -3- phenyl - 7H The psoralen derivative 8a-8o of furans [3,2-g] chromene -7- ketone (intermediate 7) and the triazole containing phenyl.And the psoralen derivative (8a-8o) of obtain 15 triazoles containing phenyl the Experiment on Function of melanogenesis and tyrosinase activity in mouse B16 cell is subjected to, it is the results show that the psoralen derivative of compound 8a, 8j, 8m-8o totally 5 triazoles containing phenyl is used equally for clinically preparing the drug for the treatment of leucoderma. |
| priorityDate | 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.