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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28
filingDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107812024-B
titleOfInvention Preparation method and application of vernonia esculenta antitumor active extract
abstract The invention provides a preparation method of vernonia galamensis anti-tumor active effective part extract, which comprises the following process steps: taking dried whole Vernonia esculenta as raw material, drying, pulverizing, adding 7-10 times of 60-95% ethanol, stirring, heating at 50-60 deg.C, reflux extracting for 1.5 hr, performing solid-liquid separation, collecting filtrate, and further adding 8 times of 60-95% ethanol into the residue; stirring, heating to 50-60 deg.C, reflux extracting for 1.5 hr, separating solid and liquid, and collecting filtrate; mixing filtrates, concentrating under reduced pressure to remove ethanol, extracting with ethyl acetate, and concentrating ethyl acetate layer to obtain extract; separating the ethyl acetate part by MCI gel resin column, eluting with 40%, 80%, 95% ethanol 7-9BV, collecting the eluate, concentrating, drying to obtain component A, component B, and component C, wherein the component B has obvious anti-tumor effect, and can be used for preparing anti-tumor drugs.
priorityDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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