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publicationDate 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107796905-A
titleOfInvention Method that is a kind of while determining bundle ten triplex pill mesaconitine of punching and its catabolite
abstract Method that is a kind of while determining bundle ten triplex pill mesaconitine of punching and its catabolite is provided the present invention relates to a kind of.Take this product appropriate, it is finely ground, take 20g, it is accurately weighed, ammonification test solution 15ml wettings, the chloroform mixed solution that adds diethyl ether (volume ratio 1: 1) 30ml, shake up, place 24 hours, filtration, the upper large pore resin absorption column of filtrate is taken, is eluted respectively with the aqueous solution and ammoniacal liquor, discards eluent, then eluted with ethanol water, collect eluent, eluent is concentrated to dryness, dissolved, produced with dichloromethane.Determined using HPLC MS methods, be capable of detecting when aconitine, benzoyl aconine, aconine and pyraconitine, the quality of ten triplex pills of punching is pricked in control well.
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Total number of triples: 63.