http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107789376-B

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http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-16
filingDate 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107789376-B
titleOfInvention Two-phase deep eutectic solvent for extracting active ingredients of ginkgo leaves and preparation method and extraction method thereof
abstract The invention discloses a two-phase deep eutectic solvent for extracting active ingredients of ginkgo leaves, a preparation method and an extraction method thereof, wherein the two-phase deep eutectic solvent consists of a hydrophilic phase and a hydrophobic phase which are equal in volume, the hydrophilic phase consists of a substance A and a substance B, the substance A consists of DES1 and water, and DES1 is prepared from choline chloride and levulinic acid; the substance B consists of DES2 and water, and DES2 is prepared from choline chloride and malonic acid; the hydrophobic phase is prepared from methyl trioctyl ammonium chloride, octanol and octanoic acid. The two-phase deep eutectic solvent prepared by the invention is a green solvent, is safe and pollution-free, has small viscosity, stable hydrogen bond and good fluidity; can simultaneously extract hydrophobic active ingredients of polyprenol acetate and hydrophilic active ingredients of ginkgetin, terpene lactone and procyanidine in the ginkgo leaves, has high extraction rate and safe use, and does not form residues. The preparation method of the deep eutectic solvent is simple and convenient, low in cost and high in biodegradability.
priorityDate 2017-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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