http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107789335-A

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filingDate 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d7774245e189cfd87b3cd3b6b73f8e2
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publicationDate 2018-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107789335-A
titleOfInvention Preparation method of artemisinin microcapsules
abstract The invention discloses a preparation method of artemisinin microcapsules. Artemisinin is dissolved in ethanol whose weight ratio is 6-8 times, then sodium starch phosphate and Tween emulsifier are added, and the core material is obtained by stirring evenly. solution; using chitosan, carboxymethyl chitosan octadecyl quaternary ammonium salt and gelatin as the wall material, adding water that is 6-8 times the weight of the wall material, warming up to 50-60 ° C, stirring evenly, to obtain the wall material material suspension; the above-mentioned core material solution and wall material suspension are added to an ultrasonic homogenizer according to a weight ratio of 1:3-5 for homogenization for 20-30min to obtain an emulsion; the emulsion is transported to a granulation sprayer for Spray-dried, cooled to room temperature, and packaged to obtain artemisinin microcapsules. The artemisinin microcapsules prepared by the method of the present invention can not only avoid the isolation of its active ingredients from the outside world, but not be affected by heat sources, light sources, air, etc., significantly improve the stability of artemisinin, significantly prolong the storage period, and can also be well preserved It contains the active ingredient of artemisinin, which is convenient for the processing, storage and transportation of artemisinin.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109875996-A
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priorityDate 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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