http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107778367-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1021 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-08 |
| filingDate | 2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107778367-B |
| titleOfInvention | Polypeptide, application thereof and medicine containing polypeptide |
| abstract | The invention provides a polypeptide, application thereof and a medicament containing the polypeptide, wherein the polypeptide can perform two-step self-assembly in series through the action of ALP and GSH to construct a nano material. The sequence of the polypeptide is NBD-GFFpYsserGD, wherein pY represents phosphorylated tyrosine, and ss represents a disulfide bond. The polypeptide can initiate a series two-step self-assembly process under the action of ALP and GSH to obtain a nano material; the simultaneous high expression of the liver cancer cells to extracellular ALP and intracellular GSH enables the polypeptide to show the strongest selectivity to the polypeptide, and can form nano-fibers in the liver cancer cells and inhibit the growth of the liver cancer cells. |
| priorityDate | 2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.