http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107778271-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D305-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D305-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107778271-B |
titleOfInvention | Synthesis method of anticancer compound CX1409 |
abstract | The invention relates to the field of organic compound synthesis, in particular to a synthesis method of an anticancer compound CX1409, wherein the anticancer compound CX1409 takes 10-acetyl baccatin III as a starting material, and 7-hydroxyl is protected by triethylchlorosilane (TESCl); then docking with a docetaxel side chain, removing a protecting group of the obtained compound by formic acid, and finally reacting with Boc anhydride to obtain a target compound CX 1409. The synthetic route provided by the invention is simple and convenient to operate, mild in reaction conditions, capable of avoiding column chromatography purification, high in yield, suitable for industrial production and wide in application prospect. |
priorityDate | 2016-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 54.