| abstract |
The present invention proposes the method for preparing desonide cream, and this method includes：(1) consistency modifiers, emulsifying agent, preservative are mixed, obtains oil phase A；(2) purified water, alkaline conditioner and stabilizing reinforcer are mixed, obtains aqueous phase B；(3) desonide is scattered in solvent, obtains aqueous phase C；(4) the oil phase A and aqueous phase B are mixed, obtains the first mixed liquor；(5) in more than or equal to 20 degrees Celsius and less than under 50 degrees celsius, first mixed liquor and aqueous phase C are mixed, to obtain the desonide cream.This method is simple, convenient, and the desonide cream prepared is while with good performance and curative effect, high-temperature stability be improved significantly, the growth of impurity is significantly inhibited. |