| abstract |
The invention relates to the field of pharmaceutical chemistry, in particular to a triazole pyridine glycine compound (I). The compound has good prolyl hydroxylase inhibition activity, can stabilize hypoxia inducible factors in cells, increases the generation and secretion of endogenous erythropoietin, and promotes the generation of red blood cells. The invention also relates to a preparation method of the compound, a pharmaceutical composition containing the compound or pharmaceutically acceptable salt thereof, and application of the compound or pharmaceutically acceptable salt thereof in preparing a medicament for inhibiting prolyl hydroxylase or preparing a medicament for promoting endogenous erythropoietin production. |