http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107753469-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-122 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-122 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-351 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P39-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107753469-B |
titleOfInvention | Application of NDGA analogue in preparing antioxidant drugs |
abstract | The invention belongs to the field of medicinal chemistry, and particularly relates to application of specific NDGA analogs in preparation of anti-oxidation medicaments and anti-ischemic stroke treatment medicaments, wherein the NDGA analogs can protect H 2 O 2 Induced PC12 cell damage, inhibition of MDA and ROS production, and obvious activation of Keap1/Nrf2/ARE antioxidant pathway, and in vivo experiment can obviously reduce rat MCAO model infarct area and improve nerve score. |
priorityDate | 2017-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 203.