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filingDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107753434-B
titleOfInvention A kind of drug-loaded liposome and the preparation method and application thereof containing hydrophilic and hydrophobic different pharmaceutical
abstract The invention discloses a kind of drug-loaded liposome and the preparation method and application thereof for containing hydrophilic and hydrophobic different pharmaceutical, liposome includes the liposome shell for containing hydrophobic components B and the liposome core for containing hydrophilic component A;Lipid bilayer is with a thickness of 4-10nm;Hydrophobic components B accounts for the 0.1%-3.4% of lipid weight;The different drug of hydrophilic and hydrophobic is loaded into liposome by the present invention, realizes hydrophilic and hydrophobic different two kinds and the above component in the procedural release of different time;And nanoparticle circulation time in blood can be extended;Preparation process is simple, convenient for production.
priorityDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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