http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107750251-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-541 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2016-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107750251-B |
| titleOfInvention | Isoxazolyl-substituted imidazopyridines |
| abstract | A compound, or a pharmaceutically acceptable salt thereof, which is an isoxazolyl imidazopyridine of formula (I): wherein R is 0 And R are identical or different and are each H or C 1‑6 An alkyl group; r 9’ And R 9” Are identical or different and are each H or F; x is- (alk) n -, -alk-C (═ O) -NR-, -alk-NR-C (═ O) -or-alk-C (═ O) -; r 1 Is selected from-S (═ O) 2 R' and an unsubstituted or substituted 4-to 7-membered heterocyclic group; r 2 And R 2' Are identical or different and are each H or C 1‑6 An alkyl group; or R 2 And R 2' Together with the C atom to which they are attached form C 3‑6 A cycloalkyl group; r 3 And R 3' Are identical or different and are each H, C 1‑6 Alkyl, OH or F; r 4 Is phenyl or a 5-to 12-membered nitrogen-containing heteroaryl group and is unsubstituted or substituted; alk is C 1‑6 An alkylene group; r' is C 1‑6 An alkyl group; and n is 0 or 1. The compounds are active in modulating the activity of p300 and/or CBP and are useful in the treatment of cancer. |
| priorityDate | 2015-04-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 280.