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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04
filingDate 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107739376-B
titleOfInvention A kind of preparation method of pa Berkeley
abstract The invention discloses a kind of preparation methods of pa Berkeley.The present invention carries out cyclization reaction using acetyl group diethyl malonate (II) and compound III and compounds Ⅳ is made; compound V is made by substitution reaction in compounds Ⅳ, and compound V carries out " one kettle way " with ethyl acetoacetate, cyclopentamine and reacts obtained finished product pa Berkeley (I).The reaction starting material is easy to get, and reaction condition is mild, easy to operate, and process route shortens, and total recovery improves, and is suitble to industrialized production.
priorityDate 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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