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filingDate 2017-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2019-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107739333-B
titleOfInvention A kind of preparation method of the quinoline compound of green
abstract The invention belongs to pharmaceutical-chemical intermediate and related chemistry technical fields, provide a kind of preparation method of the quinoline compound of green.Using N- substituted aniline derivative as raw material, Under the presence of acid catalyst and oxidant, condition of no solvent, is reacted 24 hours at 80 DEG C~160 DEG C with phenylacetylene or styrene derivative, quinoline compound can be obtained.The beneficial effects of the invention are as follows easy to operate, mild condition, it is environmental-friendly, have and realize industrialized possibility, and obtain quinoline compound with higher yields;It can further be functionalized to obtain classes of compounds using quinoline compound synthesized by this method, the exploitation and research applied to natural products, functional material and fine chemicals.
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type http://data.epo.org/linked-data/def/patent/Publication

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