http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107721912-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-61 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-61 |
| filingDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107721912-B |
| titleOfInvention | Preparation method of 2-chloro-5-methylpyridine |
| abstract | The invention discloses a preparation method of 2-chloro-5-methylpyridine, which comprises the steps of carrying out chlorination reaction on 3-methylpyridine-N-oxide serving as a raw material, 2,4, 6-triisopropyl-3-benzoyl chloride serving as a chlorinating agent and dichloromethane serving as a solvent at the temperature of-20-50 ℃ to obtain the 2-chloro-5-methylpyridine. The invention adopts 2,4, 6-triisopropyl-3-benzoyl chloride with steric hindrance effect as chlorinating agent, thus overcoming the defects of poor selectivity and low yield of 2-chloro-5-methylpyridine in the traditional method, and the yield of 2-chloro-5-methylpyridine is as high as 95 percent; in addition, the use of phosphorus oxychloride is avoided, and the defect that phosphorus-containing wastewater is difficult to treat is overcome. |
| priorityDate | 2017-11-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.