http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107715121-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-126 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G81-025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1827 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G81-02 |
filingDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107715121-B |
titleOfInvention | A kind of magnetic resonance imaging nano-medicament carrier, nano medicament carrying system and preparation method thereof |
abstract | The invention discloses a kind of magnetic resonance imaging nano-medicament carriers, nano medicament carrying system and preparation method thereof.The carrier is triblock polymer nanoparticle;The triblock polymer is PLGA-PEI-PEG, the active group in surface;The active group includes amino, hydroxyl and carboxyl.Pharmaceutical carrier of the invention can simultaneously high-efficient carrier NMR imaging drug and anti-tumor drug, make the single-minded arrival tumor focus position of anti-tumor drug, the tumor region nuclear-magnetism positioning of Superparamagnetic Fe3O4 nanoparticles is realized, while realizing highly selective, hypotoxicity therapeutic effect;Overcome that conventional cell cytotoxic drug poor selectivity, toxic side effect are relatively strong, are also easy to produce the disadvantages of drug resistance.It is of the invention that preparation method is simple, triblock polymer nanoparticle obtained can stable preservation in aqueous solution, be conducive to storage, simultaneously as particle surface there are various functional groups, is conducive to be surface modified it or surface-functionalized. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11786613-B2 |
priorityDate | 2017-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 182.