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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-19
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-105
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filingDate 2015-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107708717-B
titleOfInvention Application of rhinacanthin quinone C as nerve cell apoptosis inhibitor
abstract The invention provides a nerve cell apoptosis inhibitor, an anti-Alzheimer disease agent, an anti-cerebral hypofunction agent and a medicine with anti-Alzheimer disease or anti-cerebral hypofunction, which contains the following components as effective components: "a predetermined fraction partitioned in dichloromethane when the ethanol extract of rhinacanthus nasutus is subjected to liquid-liquid partition with hexane and methanol and the fraction partitioned in methanol is subjected to liquid-liquid partition with dichloromethane and water", "a predetermined fraction as a fraction eluted from a silica gel column by an elution solvent when the predetermined fraction is subjected to silica gel column chromatography using the elution solvent composed of n-hexane, ethyl acetate and anhydrous methanol" or rhinacanthin C. The present invention provides a neuronal apoptosis inhibitor, an anti-alzheimer agent, an anti-cerebral function-reducing agent, and a pharmaceutical agent having an anti-alzheimer effect or an anti-cerebral function-reducing effect, each of which has an excellent inhibitory effect on neuronal apoptosis.
priorityDate 2015-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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