http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107699564-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-118 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 |
filingDate | 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107699564-B |
titleOfInvention | Human prostata cancer early diagnosis long-chain non-coding RNA sequence and its application |
abstract | The present invention provides a kind of full length cDNA sequence of long-chain non-coding RNA and applications, have cloned the precise series of PRCAT38 for the first time, lay a good foundation for further function of research PRCAT38 during prostate cancer occurrence and development;PRCAT38 specificity overexpression in prostate gland cancer cell and tissue, influences proliferation, Clone formation and the migration of prostate gland cancer cell, can be used in the product for preparing the early diagnosis of prostate cancer, prognosis evaluation and/or treatment.The present invention provides a kind of cancer diagnosis markers, including PRCAT38 and EZH2 and miR-24-2, and detecting prostate has highly sensitive and high specific.The present invention provides the expression inhibiting agent of long-chain non-coding RNA, including siRNA and/or shRNA, above-mentioned expression inhibiting can inhibit the expression of PRCAT38 and EZH2 simultaneously, be conducive to the gene therapy and clinical medicine research and development of prostate cancer. |
priorityDate | 2017-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 188.