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filingDate 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107698697-B
titleOfInvention Claw-type 1, 4-triazole poly-cyclodextrin molecule and preparation method and application thereof
abstract The invention discloses a claw-type 1, 4-triazole poly-linked cyclodextrin molecule and a preparation method and application thereof, belonging to the technical field of organic synthesis; the click chemistry method is adopted, the cycloaddition reaction of the azido cyclodextrin and the alkynyl compound is carried out under the catalysis of monovalent copper ions, and the multi-link cyclodextrin with the claw-shaped three-dimensional structure is formed by connecting 1, 4-disubstituted triazole rings. The triazole ring and the central nitrogen atom of the claw-shaped 1, 4-triazole polycyclodextrin molecule form a claw-shaped structure, and the triazole ring is provided with an electricity-rich nitrogen atom, so that the triazole ring can be stably coordinated with metal, and the nano metal can be stabilized and dispersed; the claw-type 1, 4-triazole poly-linked cyclodextrin molecules have good water solubility, molecular recognition function and biocompatibility, and can be used as drug carriers and supermolecule self-assembly monomers.
priorityDate 2017-08-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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