http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107698607-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00ac7ffb74ea677895ef7881ec089a33 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D499-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C227-40 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D499-68 |
filingDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2db850c7e772ec1cade17282bc9f72ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0fd4002bb2a76c4238cfe6fbbe97d34c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e830c9eef1c49d42ab8dfba09fa58ff9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_42a391efb770d1fa903298d985e77676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daeb9c2955870cd32b25fd63d51d1325 |
publicationDate | 2018-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107698607-A |
titleOfInvention | Comprehensive Recovery Method of Active Components in Enzymatic Synthesis of Ampicillin Crystallization Mother Liquor |
abstract | The invention belongs to the technical field of pharmacy, and relates to a method for comprehensively recovering active ingredients in ampicillin crystallization mother liquor synthesized by enzymatic method. The present invention adopts the separation mode of macroporous adsorption resin to realize the separation of D-phenylglycine and ampicillin, 6-APA and D-phenylglycine methyl ester, D-phenylglycine is not adsorbed by resin, enters the adsorption residual liquid, and the adsorption residual After electrodialysis, reverse osmosis concentration, and crystallization, high-quality D-phenylglycine is recovered; and ampicillin, 6-APA and D-phenylglycine methyl ester adsorbed on the resin are analyzed and then concentrated by nanofiltration. The obtained nanofiltration concentrate can be directly used as the reaction bottom water in the ampicillin enzymatic synthesis process and then recovered and used mechanically. The present invention comprehensively recovers the active ingredients D-phenylglycine, ampicillin, 6-APA and D-phenylglycine methyl ester in the enzymatic ampicillin crystallization mother liquor, creates economic benefits, reduces the discharge of high-concentration waste water at the same time, and realizes Environmentally friendly, clean and green production. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111393315-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111393315-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108773924-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108773924-A |
priorityDate | 2017-08-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.