| abstract |
The present invention relates to polyvinyl alcohol/collagen/n-trimethyl chitosan chloride electrospun composite fibers film and preparation method thereof, belong to medical instruments field.Preparation method：First by adjusting the mass ratio and concentration of polyvinyl alcohol and collagen, the pattern of spinning fibre is evaluated, determines the optimal proportion 80 of polyvinyl alcohol and collagen:20, optium concentration 8%；Then, when addition n-trimethyl chitosan chloride concentration is 5%, polyvinyl alcohol/collagen/n-trimethyl chitosan chloride electrospun composite fibers film is made by electrostatic spinning technique.The composite fibre film preparation of the present invention is easy; with good pliability and mechanical property; being capable of quick-acting haemostatic powder; and the fibrofelt of protective can be formed in wound surface, promotes wound reparation, prevents bacterium infection; so as to cure skin injury; have both the functions such as hemostasis, antimicrobial antiphlogistic, wound repair, be well suited as hemostasis, wound repair, medical equipment material, there is good application prospect. |