| abstract |
The invention provides a method for establishing a rhesus monkey hepatic fibrosis model by an intraperitoneal injection method, which comprises the following steps: selecting male rhesus monkeys of 2-3 years old and 5-9kg weight as model animals, feeding high-fat feed with 9-11% alcohol water solution in molding process, and injecting CCl into each rhesus monkey in molding process 4 The animal model is established by simple method, safety and reliability, short modeling time, high success rate, good repeatability, good animal tolerance and low mortality, and can be used for researching the occurrence mechanism, pathogenic factors and treatment means of chronic liver diseases. |