http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107693487-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-216 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-216 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 |
| filingDate | 2017-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-03-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107693487-B |
| titleOfInvention | Anthracycline antitumor antibiotic compound micelle and preparation method and application thereof |
| abstract | The invention discloses a compound nano micelle simultaneously carrying anthracycline antitumor antibiotics and salvianolic acid A, and a preparation method and application thereof. The compound micelle comprises effective dose of anthracycline antitumor antibiotic, salvianolic acid A and amphiphilic high molecular polymer, and two medicines are stably wrapped in the nano micelle together in a simple physical wrapping mode through the combined action of electrostatic attraction between a basic group of the anthracycline antitumor antibiotic and an acid group of the salvianolic acid A and self-assembly of the amphiphilic high molecular polymer in an aqueous medium, so that the obtained compound micelle is uniform in particle size, the wrapping rate is more than 95%, and the drug loading rate and the stability are obviously superior to those of single-medicine micelle. |
| priorityDate | 2017-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.