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filingDate 2017-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2020-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107688060-B
titleOfInvention Detection method of fluticasone propionate nasal spray
abstract A method for detecting fluticasone propionate nasal spray relates to the field of medical detection, and comprises the steps of spraying the fluticasone propionate nasal spray to be detected into a container, adding a solvent for dissolving, adding a sodium chloride solution, adding the solvent for constant volume, shaking up and centrifuging, and taking supernate as a test sample solution; weighing a fluticasone propionate reference substance, adding a solvent to dissolve and fixing the volume to be used as a reference substance solution; respectively measuring a test solution and a reference solution, injecting into a liquid chromatograph for chromatographic analysis, and recording a chromatogram; according to the chromatogram, the content of the fluticasone propionate in the test solution is calculated by the peak area according to an external standard method, so that the content of the fluticasone propionate in the fluticasone propionate nasal spray is calculated, the detection method can detect the content of the fluticasone propionate in each time of the fluticasone propionate nasal spray, and therefore the uniformity of the delivered dose is detected, and the method is simple and effective.
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