http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107686494-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H7-033 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H7-033 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 |
| filingDate | 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107686494-B |
| titleOfInvention | Indoloquinolizine-6-hydroxymethyl-glucuronate, preparation, activity and application thereof |
| abstract | The invention provides (6S) -3-acetyl-6-hydroxymethyl-4, 6,7, 12-tetrahydro-4-oxoindole [2, 3-alpha ] quinolizine-alpha-D-furoglucuronate, provides a preparation method thereof, discloses antitumor activity of the compound on a mouse S180 transplantation sarcoma model, discloses antitumor transfer activity of the compound on a mouse Lewis lung cancer transfer model, discloses anti-inflammatory action of the compound on a mouse ear swelling model, and further discloses antithrombotic action of the compound on a rat common carotid artery-external jugular vein circulation bypass wire method antithrombotic model. Therefore, the invention discloses the application of (6S) -3-acetyl-4-oxo-4, 6,7, 12-tetrahydroindolo [2, 3-alpha ] quinolizine-6-hydroxymethyl-glucuronate in preparing antitumor drugs, antitumor lung cancer metastasis drugs, anti-inflammatory drugs and antithrombotic drugs. |
| priorityDate | 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 320.