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filingDate 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b49d7336e115bc642c1d7c86beef2c65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_310205baf5c2fc3564c67a26b238d27f
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publicationDate 2018-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107684626-A
titleOfInvention The purinethol cisplatin nano grain of mesoporous silicon oxide 6, it is prepared, activity and application
abstract The invention discloses a kind of nanometer delivery system (MSNS 6MP/CDDP) of the purinethol of mesoporous silicon oxide 6 (6MP) of Nano grade/cis-platinum (CDDP).Disclose its preparation method, sulfydryl is modified on mesoporous silicon oxide, connection 6MP mesoporous silicon dioxide nano particle (MSNS 6MP) is formed by disulfide bond 6MP, CDDP is loaded into duct, connection 6MP is formed, loads CDDP mesoporous silicon dioxide nano particle;Disclose its nanostructured;The effect that it suppresses S180 mice tumors grews is disclosed, compared with conventional 6MP and CDDP use in conjunction, MSNS 6MP/CDDP significantly extend the life span of S180 mouse, improve curative effect and reduce general toxic reaction.Thus the invention discloses its application in anti-tumor medicine is prepared, there is good application prospect.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114748641-A
priorityDate 2016-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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