http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107674085-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08 |
| filingDate | 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107674085-B |
| titleOfInvention | A method for synthesizing 1, 5-epoxy-2, 3,4, 5-tetrahydro-1H-1-benzazepine derivative |
| abstract | The invention discloses a 1, 5-epoxy-2, 3,4, 5-tetrahydro-1H-1-benzazepine The synthesis method of the derivative comprises the step of reacting benzisoxazole shown as a formula I with substituted cyclopropane shown as a formula II under the promotion of catalytic amount of Lewis acid to obtain 1, 5-epoxy-2, 3,4, 5-tetrahydro-1H-1-benzazepine shown as a formula III The derivative has the following reaction formula, wherein R is 1 Is hydrogen, halogen, alkyl, alkoxy or aryl; r 2 Is aryl, alkyl or alkenyl; r 3 And R 4 Each independently is an electron withdrawing group. The synthesis method has the advantages of mild reaction conditions, simple operation and good diastereoselectivity. |
| priorityDate | 2017-04-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.