http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107669622-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 |
| filingDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107669622-B |
| titleOfInvention | Bivalirudin injection and preparation method thereof |
| abstract | The invention provides a bivalirudin injection and a preparation method thereof, wherein the bivalirudin injection comprises bivalirudin, trehalose, a pH regulator, an osmotic pressure regulator and an excipient; wherein the pH regulator is pharmaceutically acceptable sodium hydroxide, the osmotic pressure regulator is pharmaceutically acceptable sodium chloride or glucose, and the excipient is water for injection. The invention improves the stability of the bivalirudin aqueous solution stored for a long time at room temperature, avoids the multiple transfer processes of the product in the redissolution and dilution processes of the existing bivalirudin sterile lyophilized powder injection in clinical use, and improves the safety of the bivalirudin clinical medication. |
| priorityDate | 2016-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 40.