http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107652341-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-073 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107652341-B |
| titleOfInvention | A kind of improved method preparing " Trifluridine " |
| abstract | The present invention relates to a kind of methods for preparing " Trifluridine " (Trifluridine, Viroptic).The method has main steps that: with uridine (compound shown in Formula II) for starting material, successively the esterification through perhydroxyl radical and halogenation, reduction reaction, trifluoromethylation reaction and the reaction of deprotection group and etc. obtain object.Method provided by the invention has many advantages, such as to avoid the reagent using expensive raw material and high toxicity and pollution environment, and respectively step reaction condition is mild.Therefore, the present invention provides a kind of green, safety and the preparation methods of " Trifluridine " that has business preparation value. |
| priorityDate | 2017-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 93.