| abstract |
The present application discloses a compound of formula (I) or a salt thereof, wherein: X is N; W is: -(CR 3 R 3 ) 2-5 -, -(CR 3 R 3 ) x -Y-(CR 3 R 3 ) y ‑, ‑Y‑(CR 3 R 3 ) 2‑3 ‑Y‑, ‑CR 3 R 3 ‑Y‑(CR 3 R 3 ) 2 ‑Y‑, ‑Y‑(CR 3 R 3 ) 2 -Y-CR 3 R 3 -; and Y, R 1 , R 2 , R 3 , R 5 , R 6 , R 8 , x and y are defined herein. The application also discloses methods of using the compounds as modulators of TNFα, as well as pharmaceutical compositions comprising the compounds. These compounds are used in the treatment of inflammatory and autoimmune diseases. |