http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107629111-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-11 |
| filingDate | 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107629111-B |
| titleOfInvention | Liquid phase synthesis method of acetyl tetrapeptide-2 |
| abstract | The invention discloses a liquid phase synthesis method of acetyl tetrapeptide-2, which synthesizes 2N-terminal or side chain protection small-fragment peptides by a liquid phase synthesis method: Ac-D-Lys (Boc) -Asp (OtBu) -OH and H-Val-m-Tyr-OMe, condensing small-fragment peptide, finishing carbon-terminal amidation through ester exchange to obtain a target product with protection, deprotecting to obtain a crude product of acetyl tetrapeptide-2, and purifying the crude product to obtain a pure product of acetyl tetrapeptide-2. The synthetic method of the invention avoids the use of expensive resin in a solid phase method, overcomes the defects that the solid phase method uses protected amino acid in each step and uses too much reagent, reduces the cost, and has the advantages of simple synthetic method, energy saving, environmental protection and the like. |
| priorityDate | 2017-10-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.