http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107625960-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39 |
| filingDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107625960-B |
| titleOfInvention | Universal swine colibacillosis vaccine and preparation method thereof |
| abstract | The invention provides a universal swine colibacillosis vaccine and a preparation method thereof, belonging to the technical field of animal bacteria genetic engineering. The vaccine contains the following antigens: the fusion protein formed by periplasm chaperone protein Skp, MltA-related protein MipA and long-chain fatty acid outer membrane transporter Lomt, the B subunit of heat-labile enterotoxin and the B subunit of Shiga toxin 2e, wherein the sequences of the antigens are respectively shown as SEQ ID NO. 4, SEQ ID NO.5 and SEQ ID NO. 6. After the universal swine colibacillosis vaccine is immunized, animals can generate higher IgG and IgA antibodies, and the antibody duration exceeds 120 days. After the vaccine is immunized, the attacks of ETEC F4, F5, F6, F41 and O139 can be simultaneously protected, the protection rate is 100%, the diarrhea phenomenon does not occur, and the protection range is remarkably expanded compared with the existing vaccine. |
| priorityDate | 2017-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 403.