http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107604006-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2017-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107604006-B |
| titleOfInvention | Stabilizer for clinical-grade lentivirus and use method thereof |
| abstract | The invention relates to the field of biochemical medicine, in particular to a stabilizer for clinical lentivirus and a use method thereof, wherein the stabilizer for clinical lentivirus comprises 10-20g/ml of sucrose, 40-100mg/L of tocopherol, 10-20g/ml of human serum albumin and the balance of 0.01mol/L of PBS buffer solution with pH7.4, and is obtained by filtering through a 0.22 mu m filter. The application method of the stabilizer for clinical lentivirus is that the clinical lentivirus suspension and the stabilizer for clinical lentivirus are gently mixed according to the volume ratio of 9:1, subpackaging is carried out, and the subpackaged clinical lentivirus suspension is stored at the temperature of-80 ℃. The verification proves that the titer of the lentivirus is not reduced at all after the lentivirus is stored for 6 months at the temperature of-80 ℃, the titer is not obviously reduced after one freeze thawing, the titer loss is only 10 percent after three freeze thawing, and the method meets the storage requirements of the lentivirus in the production, transportation and use processes. The invention has simple components, few using steps, no need of additional instruments and equipment, easy quality control and accordance with the requirements of clinical application. |
| priorityDate | 2017-09-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 16.