http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107603982-B
Outgoing Links
Predicate | Object |
---|---|
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P15-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
filingDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107603982-B |
titleOfInvention | Method and kit for diagnosing male sterility caused by Piwil1 gene mutation |
abstract | The invention relates to a method and a kit for diagnosing male sterility caused by Piwil1 gene mutation. The invention discloses a gene related to male sterility such as azoospermia, namely Piwil1 gene. Moreover, multiple mutations of Piwil1 gene were identified to cause male infertility. Therefore, the Piwil1 gene can be used as a target gene for diagnosing male infertility and can be applied to the development of therapeutic drugs effective for the above-mentioned diseases. The present invention also provides for the first time an explanation of the mechanism by which PIWIL1 participates in the replacement of histone by protamine. |
priorityDate | 2016-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 88.