http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107602615-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-60 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-6561 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2016-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2019-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107602615-B |
| titleOfInvention | Quinolinone phosphate derivative and its preparation method and application |
| abstract | The invention discloses a kind of quinolinone phosphate derivatives and its preparation method and application.The derivative is to take 3- carboxaldehyde radicals -2 (1H)-quinolinone and (4- Amino-benzyl)-diethyl phosphate to be dissolved in toluene to be placed in heavy wall pressure bottle, at being 120 DEG C in temperature, is stirred to react and obtains.Derivative anti-tumor drug 5-FU more common to the inhibitory activity of human liver cancer cell HepG2 is higher, and lower to people's normal cell lines of human liver HL-7702 toxicity.The structural formula of derivative of the present invention is as follows: |
| priorityDate | 2016-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.