http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107602451-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06 |
filingDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107602451-B |
titleOfInvention | Triangular electron push-pull mitochondrial targeting detection SO2Fluorescent probe and preparation method and application thereof |
abstract | The invention relates to a 'triangular electron push-pull' mitochondria targeted detection SO 2 The fluorescent probe and the preparation method and the application thereof. The 4-hydroxy m-phthalaldehyde is obtained by dissolving phenol in toluene and glacial acetic acid under the catalysis of hexamethylenetetramine. Then 4-methylpyridine, diethyl ether and methyl iodide are stirred at normal temperature to obtain the 1, 4-dimethylpyridine iodide salt. The 4-hydroxy isophthalaldehyde and 1, 4-dimethylpyridine iodide salt react under the protection of nitrogen by using ethanol as a solvent and piperidine as a catalyst to obtain the fluorescent probe FHMI. The probe overcomes the problem that an electron-donating group is separated from a conjugated system caused by the detection of a substance to be detected by nucleophilic reaction. FHMI is suitable for SO in biological samples 2 The qualitative and quantitative analysis is carried out, and the detection is sensitive, accurate and quick; can be applied to the related fields of analytical chemistry, life organic analytical chemistry and the like. |
priorityDate | 2017-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.