http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107596452-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B37-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C01B33-12 |
| filingDate | 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107596452-B |
| titleOfInvention | Preparation method and application of intelligent antibacterial coating sensitive to bacteria |
| abstract | The invention discloses a preparation method and application of a bacteria-sensitive intelligent antibacterial coating, and belongs to the field of composite antibacterial materials. Firstly, synthesizing a mesoporous silica film with a two-dimensional pore channel vertical to a substrate; secondly, carrying out organic functional modification on the surface of the silicon dioxide film; finally, the modified film and the macrocyclic molecules form a nano valve together to encapsulate the antibacterial drug. When the bacteria infect a host, the bacteria secrete a series of pathogenic factors to form special bacterial infection micro-environments, and the special micro-environments are used as stimulating factors to promote the drug-loaded nano-containers to release drugs, so that the selective delivery of antibiotics is realized. The strategy can obviously increase the selectivity and the drug effect of antibiotics, reduce the toxic and side effects of the drugs, and maintain the infected part at a higher drug concentration, thereby overcoming the drug resistance of the antibiotics. |
| priorityDate | 2017-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 72.