http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107586793-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-02 |
filingDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2020-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107586793-B |
titleOfInvention | Method for preparing alcohol compounds having multiple chiral centers |
abstract | Disclosed is a method for preparing an alcohol compound having a plurality of chiral centers. The method comprises the following steps: is reacted in a reaction system under the action of ketoreductase to generate Wherein R is 1 、R 2 Each being methyl or ethyl, R 3 Is tert-butyloxycarbonyl or benzyloxycarbonyl, n-0 or 1. By applying the technical scheme of the invention, the ketoreductase takes ketone compounds as raw materials, can efficiently produce chiral alcohol through stereoselective reduction, can be selectively split, and can obtain chiral alcohol compounds with a plurality of chiral centers in one step; and the substrate is relatively cheap, the product purity is high, suitable for popularizing and using in the industrial production of chiral alcohol. |
priorityDate | 2017-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 831.