http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107569454-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-335 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-08 |
| filingDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107569454-B |
| titleOfInvention | A kind of Olopatadine hydrochloride nasal spray and preparation method thereof |
| abstract | The invention belongs to pharmaceutical technology field, a kind of Olopatadine hydrochloride nasal spray and preparation method thereof is provided, the nasal spray is made of Olopatadine hydrochloride, water soluble chitosan, chitosan quaternary ammonium salt, hydroxypropyl beta cyclodextrin, osmotic pressure regulator, buffer, pH adjusting agent and purified water.Olopatadine hydrochloride nasal spray provided by the invention extends holdup time of the Olopatadine hydrochloride in nasal cavity, improve the bioavilability of Olopatadine hydrochloride, in addition, also improve the stability of product and reduce product bitter taste, nose is bleeding, the incidence for the adverse reaction such as have sore throat, it is low to schneiderian membrane irritation, Small side effects, improve the security of nasal cavity applied medicine. |
| priorityDate | 2017-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.