http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107569447-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fab935ecd7c66d7b5581b27ed13cc51d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-18 |
| filingDate | 2017-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5044c4f4bf60b5736d209758cb3e8c0f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f2cbd2c1fd2f574afa5d4286a5247c2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c064d89a8d07a415953769501f7a7d95 |
| publicationDate | 2018-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107569447-A |
| titleOfInvention | It is loaded with soluble microneedle patch of purified protein derivative of tuberculin and preparation method thereof |
| abstract | The present invention relates to a kind of soluble microneedle patch for being loaded with purified protein derivative of tuberculin and preparation method thereof, the soluble microneedle patch includes substrate and needle body, and the substrate is prepared by the first high polymer material；The needle body is prepared by combining rhzomorph purified protein derivative and needle body excipient material；The percentage that the combination rhzomorph purified protein derivative accounts for needle body gross weight is 0.04 0.10%；The needle body excipient material includes the second high polymer material and small molecule material；Second high polymer material is selected from least one of hyaluronic acid or its sodium salt, HES, polyvinylpyrrolidone and polyethylene glycol；The small molecule material is selected from water miscible small molecular sugar, the water-soluble amino acids of slant acidity, at least one of the water soluble salt of slant acidity；The mass ratio of second high polymer material and small molecule material is 38:1.The soluble microneedle patch of the present invention has good puncture strength and internal dissolution velocity. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112023033-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112023033-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-108888577-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111053715-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110947088-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112274633-A |
| priorityDate | 2017-09-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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