http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107561268-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-577 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-76 |
filingDate | 2017-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2019-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-107561268-B |
titleOfInvention | A chemiluminescence immunoassay based on smart nanoluminescent particle labeling amplification and its application |
abstract | The invention discloses a chemiluminescence immunoassay method based on intelligent nano-luminescence particle labeling amplification and its application. It includes covalently coupling an antibody of the antigen to be tested to the carboxyl group on the surface of the intelligent nanoluminescent particle to form an intelligent nanoluminescent particle with amplifying labeling effect; directly or indirectly coating another antibody of the antigen to be tested On the solid phase carrier, add the intelligent nanoluminescent particles and the sample containing the antigen to be tested, through the interaction of the antibody-antigen-antibody, the solid phase carrier-antibody-antigen to be tested-antibody-smart nanoluminescent particle immunocomplexation is formed After separating the immune complex, add the exciter, and detect the luminescence intensity with a chemiluminescence detector to calculate the concentration of the antigen to be tested. The invention can improve the labeling efficiency of luminescent molecules and antibodies, and enhance the luminescence intensity. The present invention has the advantages of high sensitivity and wider detection range. |
priorityDate | 2017-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 253.