abstract |
The application is related to the method for separating and detecting minodronic acid, this method passes through high performance liquid chromatography, using reverse-phase chromatographic column, using the buffer solution of the pH containing sodium alkyl sulfonate=2 7.5 as mobile phase A, using methanol or acetonitrile as Mobile phase B, Detection wavelength is 215nm, is separated and is detected using linear gradient elution mode. |