http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107540689-A

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Predicate Object
assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_43e689f175057f56c04ebbccf59f8abe
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-20
filingDate 2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67ed59aa9323b13d69695d99655f3863
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ed6916aed606c425f5532d466226762
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04720ccdddccec697c850d93ba7c9630
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c13f267f348e30979b2eba48370362b1
publicationDate 2018-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-107540689-A
titleOfInvention Synthetic method of antitumor drug
abstract The invention relates to a method for synthesizing antitumor drugs. The synthetic method of this antitumor drug adopts structural formula: Compound A was used as the initial reactant, and combined with the efficient intramolecular [4+2] cycloaddition reaction and the key cerium ammonium nitrate oxidation [3+2] reaction, the molecular skeleton structure was quickly constructed, and the structural formula was The antineoplastic drug has the same structure as the natural product (‑)‑Hypocrolide A. The synthesis method of the above-mentioned anti-tumor drug obtains a high-yield anti-tumor drug through chemical synthesis, reduces the production cost of (-)-Hypocrolide A, and increases the source of (-)-Hypocrolide A.
priorityDate 2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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isDiscussedBy http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID465472519

Total number of triples: 14.