http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107540685-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D309-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D493-04 |
| filingDate | 2017-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2020-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107540685-B |
| titleOfInvention | Preparation method and intermediate of Sotagliflozin |
| abstract | The preparation method of the Sotagliflozin provided by the invention is to improve the structure of the L-xylose derivative 1, and the hydroxyl is protected by benzyl or PMB groupThe compound 2 or the compound 2 obtained by carrying out series derivatization reaction on the L-xylose derivative 1A, and the Grignard docking reaction conditions of the compound and the 4-halogeno-1-chloro-2- (4-ethoxybenzyl) benzene compound 3 are optimized, so that the reaction yield is improved to over 85 percent, the use of excessive Grignard reagents or lithium reagents is avoided, the material consumption is reduced, and the route efficiency is improved. |
| priorityDate | 2017-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 172.