http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107531792-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_222621aacfd8c8dcec07257efb9e6f90 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21004 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B30-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 |
| filingDate | 2016-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c50fa38662fd8b5b7976f3086d9556fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3dff48f070165e51705d489ee20fb0ec |
| publicationDate | 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-107531792-A |
| titleOfInvention | A new method for epitope selection |
| abstract | The present invention relates to certain novel methods of selecting epitopes for antibodies. The invention also provides methods of producing antibodies (e.g., functional antibodies) against proteins, the methods comprising: (i) identifying antigenic epitopes in the protein by contacting the protein with at least one protease to exposing the protein to restricted or constrained proteolysis by forming at least one digested, deconstructed or truncated version of the protein and at least one surface-exposed peptide that is removed from the protein by the action of the protease cleavage on the protein, and an epitope is generated based on the surface-exposed peptide; and (ii) raising antibodies against the epitope. The invention also provides antigenic epitopes and antibodies directed against such epitopes. |
| priorityDate | 2015-03-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 967.