| abstract |
Substituted benzoxaboroles are provided, the structure of which comprises formula (III), wherein R 3 is selected from -CH 3 , -CH 2 CH 3 , -CH 2 =CH 2 , -CH 2 CH 2 CH 3. -CH(CH 3 ) 2 , -CH 2 CH 2 =CH 2 and cyclopropyl; and R 1 and R 2 are each independently selected from H, -CH 3 , -CH 2 CH 3 , -CH 2 CH 2CH3 and -CH( CH3 ) 2 ; compositions containing the compounds, their use in therapy, including their use as antimycobacterial agents, for example for the treatment of mycobacterial infections in mammals uses, and methods of preparing such compounds. (III). |