abstract |
An aromatic amide derivative shown in general formula (I), its preparation method, a pharmaceutical composition containing the derivative, its use as a ROR regulator and its prevention and/or treatment of inflammation, autoimmune diseases and Use in diseases such as cancer. The aromatic amide derivatives have agonistic or inverse agonistic activity on ROR. The combination of the arylamide derivatives and the PD-1 antibody can be used for the treatment of tumors or cancers. |