abstract |
The present invention is directed to storage stable formulations of long RNAs. In particular, the present invention relates to dry powder compositions comprising long chain RNA molecules. The present invention is also directed to methods of preparing dry powder compositions comprising long chain RNA molecules by spray lyophilization. The present invention also relates to the use of this dry powder composition comprising long-chain RNA molecules in the preparation of pharmaceutical compositions and vaccines, methods for treating or preventing diseases or diseases, the first and The second medical application, and the kit, especially the kit including this dry powder composition containing long-chain RNA molecules. |